Before building the CoLBeRT system, Andrew Leifer first built this prototype that works with pretend worms as a proof-of-principle. In this case the pretend worm is a an 8.5" by 11" printout of a picture of the nematode C. elegans. The software finds the worm, tracks it, and shines light on only a specific region of the worm. This early demonstration formed the basis for what grew into the CoLBeRT system.

For more information see: colbert.physics.harvard.edu

Leifer et al, "Optogenetic manipulation of neural activity in freely moving C. elegans," Nature Methods, in press, 2011.

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