Yes. I resorted to tools in my Facebook poking battle with Kelley Koehler ( @housechick ). Quite frankly, the woman is a machine. I tried to keep up using txt on my my iphone and was unable to keep up and maintain a sense of sanity at the same time.
So, I turned to an Autopoke script for Greasemonkey devilsworkshop.org/facebook-autopoke-script-poke-back-all-at-once/ and an auto-refresh plugin reloadevery.mozdev.org
Kelley... you are the Queen of Poking. I bow to you. The only way to beat you is to cheat. :)
twitter.com/housechick
facebook.com/profile.php?id=718145545&v=feed&story_fbid=41408441495
(I have deleted the autopoking script) :)