TrueCrypt is a great tool for securing sensitive data. However, your security is dependent on your password - and most of us are poor at creating truely strong passwords - and if we do, they are long and difficult to enter.
The YubiKey re-programmed for static passwords (vimeo.com/3038098) generates a 44 character password containing 176 bits of randomness. Watch this video to see it in action with TrueCrypt and go to yubico.com to buy one.