Carolyn Bertozzi, University of California, Berkeley
Protein are the most prevalent biomolecules in living cells and participate in every cellular process. They are encoded by the cell's DNA, which is transcribed into RNA and ultimately translated into proteins. Thereafter, proteins can be posttranslationally modified in various ways, including phosphorylation and glycosylation. These modifications can modulate the structure and activity of the underlying protein, providing Nature with diverse ways of controlling protein function. This session will focus on chemical approaches for modulating the functions of proteins. The chemical tools presented can help biologists understand how proteins function within cells, as well as point to new directions for drug development.
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