It’s been two months since the escaped drug dealer spread the virus onto the streets of Seattle and more than 100,000 have died as a result. On his way to the gym Agent Jack Kane is captured by a Kayloran agent and placed in a cargo container with a bomb. Meanwhile Natalie discovers her and Colin are about to have a baby. Agent Caitlyn Adair discovers her children have been infected with the virus. Will Jack escape before the bomb goes off? Will medical science find a cure in time to save Adair’s children?