Dr. Thomas Martin, director of the Myeloma Institute at UCSF Medical Center, explores how various therapies are chosen for the treatment of multiple myeloma. Dr. Martin begins by discussing how myeloma progresses and also explains the clinical manifestations of myeloma known as CRAB (elevated calcium, renal insufficiency, anemia, and bone lesions), which helps experts to evaluate whether the disease is transforming beyond watch and wait. Dr. Martin makes it clear that each therapy approach—whether it is a stem-cell transplant or maintenance therapy—is based on personalized care.

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