The Nijmegen Centre for Molecular Life Sciences (NCMLS) is a leading multidisciplinary research school within the domain of molecular mechanisms of disease and particularly in the fields of molecular medicine, cell biology and translational research. The NCMLS accommodates research groups from the Radboud University Nijmegen Medical Centre and the Faculty of Science at the Radboud University Nijmegen. Our research is focused along three main research themes in keeping with our mission towards ‘Understanding the cellular basis of disease'.