Since the demise of rival station KSJO in 2004, the station has adopted a mainstream rock format. Bands in their playlist range from classic rock such as The Rolling Stones, Pink Floyd, The Who, and Led Zeppelin, southern rock such as Lynyrd Skynyrd and The Eagles, alternative rock, punk rock, or grunge like Alice in Chains, Nirvana, Pearl Jam, Stone Temple Pilots, The Offspring and Green Day, and hard rock and heavy metal music such as Rush, Van Halen, Metallica, Black Sabbath, and AC/DC. Morning personalities Lamont & Tonelli are on the air weekdays from 5-10 AM, with highlights of the week replayed Saturdays 6-10 AM. In addition, on weekdays, the station provides traffic reports for the San Francisco Bay Area every 15 minutes from 5AM to 10AM and from 3PM to 7PM. The 5:00 PM hour is dedicated to a set of live songs from a particular artist. KSAN also plays a select Led Zeppelin song at the top of the 7:00 PM hour on the weekdays.
Throughout the NFL season, the station broadcasts San Francisco 49ers games. In April 2007, the station broadcast two away games Golden State Warriors basketball team - April 6 at the Memphis Grizzlies and the next being April 13 at the Sacramento Kings.  Normally, Warriors games are broadcast on the San Francisco sports station KNBR.
KSAN also broadcasts in HD with the following Stations
HD-1 107.7 The Bone
HD-2 The Bone 2 (Active Rock)