The abstract organized into this and the following two videos highlights two recent papers from authors at the University of California, San Francisco working within the Princeton Physical Sciences Oncology Center. In this video, we review examples of ways that the timings of biochemical reactions can appear to be random.
Liao D, Estévez-Salmerón L, and Tlsty T D 2012 Conceptualizing a tool to optimize therapy based on dynamic heterogeneity† Phys. Biol.9(6):065005 (doi:10.1088/1478-3975/9/6/065005) (open-access online)
Liao D, Estévez-Salmerón L, and Tlsty T D 2012 Generalized principles of stochasticity can be used to control dynamic heterogeneity Phys. Biol.9(6):065006 (doi:10.1088/1478-3975/9/6/065006) (open-access online)
† The authors dedicate this paper to Dr Barton Kamen who inspired its initiation and enthusiastically supported its pursuit.
The research described in these articles was supported by award U54CA143803 from the US National Cancer Institute. The content is solely the responsibility of the authors and does not necessarily represent the official views of the US National Cancer Institute or the US National Institutes of Health.
(C) 2012-2013 David Liao (lookatphysics.com) CC-BY-SA (license updated 2013 March 27). When distributing this set of three videos under the Creative Commons license, please cite the full journal references above (including authors and dois) as well as the citation information for this video collection:
Title: Dynamic heterogeneity for the physical oncologist
Author of work: David Liao
The full citation of the papers (at least the first paper) is necessary because the journal Phys. Biol. has released these works under a CC-BY-NC-SA license. These papers are copyrighted and not public domain.