On the site where St. Frances Cathedral stands today there was originally a small mission church. That mission was burned down in the Pueblo Revolt of 1680. After the Spanish regained control in 1692, a more substantial adobe church, La Parroquia, was built on this site. That church served for almost 200 years.
More at http://two.archiseek.com/2010/1884-st-francis-cathedral-santa-fe-new-mexico/