So here is another test. I'm actually working these fluid effects into a really project. Cool huh? The fluid is 250 res. I'm using several emitters for the blast. That go off at different frames to make it feel a little more realistic. Also there is a volume axis field pushing some of the fluid on the ground.
Note this has nothing to do with any political, natural, or man-made disaster. I'm just trying to make a simpler setup to make rendering a bit easier.