Tourette Disorder (TD) is defined by having both multiple motor and vocal tics that last for more than one year and onset is typically in early childhood. Tics are sudden, rapid, repeated, non-rhythmic movements (motor tics) or vocalizations (vocal tics). TD is a poorly understood, often debilitating disorder affecting as many as one in a 100 individuals worldwide. For many people, the media has negatively altered the perception of TD. While only a small fraction of individuals with TD experience complex vocal tics such as cursing, many patients have other complex or simple motor or vocal tics as well as obsessive-compulsive disorder (OCD) and/or attention-deficit/hyperactivity disorder (ADHD) that cause long-lasting impairment. Currently, there is no effective, specific treatment for TD. Drs. Gary Heiman and Jay Tischfield at Rutgers University, are seeking to uncover the genetic causes of TD with the hope of developing effective treatments that could improve ameliorate patients’ quality of life and restore productivity. Additionally, since TD is frequently associated with OCD, ADHD, anxiety, and depression, understanding genetic mechanisms of causality might also shed light on those often debilitating mental disorders.