David Shattuck (http://bit.ly/qWdhpD) presents a survey of the rapidly evolving field of biomedical imaging, and includes some stunning images from his own work on brain imaging. He also discusses the role played by data visualization, which is critical in diagnosis, validation, and interpretation. He identifies the key challenges as keeping apace with increasing data complexity, size, and interconnectedness. This talk was presented at VIZBI 2011, an international conference series on visualizing biological data (vizbi.org) funded by NIH & EMBO. This video was filmed and distributed with permission under a creative common license.