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An American Werewolf in London is a 1981 British-American horror comedy film, written and directed by John Landis. It stars David Naughton, Griffin Dunne, and Jenny Agutter.

It was released in the United States on August 21, 1981 and grossed $30.56 million at the box office. Critics generated mostly favourable reviews for the film. The movie won the 1981 Saturn Award for Best Horror Film and an Academy Award for Outstanding Achievement in Makeup. The film was one of three high-profile wolf-themed horror films released in 1981, alongside The Howling and Wolfen.

The opening shots of the moors are near Hay Bluff, a mountain that straddles the Welsh border in Brecon Beacons National Park. The scenes were shot on the Welsh side of Hay Bluff, about four miles to the south of the town of Hay-on-Wye in the county of Powys. The scene where David and Jack get dropped off by the sheep farmer is by the stone circle, the same location where, later in the film, Dr. Hirsch stops and looks at the sign for East Proctor. The same road provides the scenery for the next two shots, where David and Jack talk about Debbie Klein.

East Proctor is a small hamlet ten miles to the west of Hay Bluff called Crickadarn. It is featured from the shot where David and Jack walk down a hill towards East Proctor. The exterior of the "Slaughtered Lamb" was a private house in Crickadarn dressed to look like a pub and the Angel of Death statue in the village was a prop created by the movie makers. The church next door is also still frequented, however the upper levels have now fallen into disrepair.

The interior of the "Slaughtered Lamb" was filmed in a pub called The Black Swan, Ockham, Surrey near Effingham. The bar was used but a false wall was built to make the pub look smaller. The Black Swan was re-furbished and extended to became a gastro pub in 2006 making it unrecognisable from the interior used for the film.

Nurse Alex's flat is located on Coleherne Road, just off Redcliffe Square (SW10), Kensington near to Earl's Court.

The attack at the tube station was set in — and filmed at — Tottenham Court Road tube station .

The final sequence in the alleyway was filmed at Clink Street, London. The location is now almost unrecognisable, the area having been redeveloped since.

The scenes where David wakes up naked in the zoo were shot at London Zoo, Regent's Park.

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