Join us for a fascinating discussion with Dr. Aubrey de Grey, Chief Science officer of the SENS Foundation (SENS stands for “Strategies for Engineered Negligible Senscence”), on the topic of “Regenerative Medicine Against Aging.”
Dr. de Grey has been a provocative and polarizing figure in the scientific and medical communities’ dialogue on the topic of life extension, and the approaches that will lead to dramatic increases in quantity and quality of life.
According to Dr. de Grey, “the first human who will live up to 1,000 years is probably already alive now, and might even be today between 50 and 60 years old.”
Dr. Aubrey de Grey is a biomedical gerontologist based in Cambridge, UK, and is the Chief Science Officer of SENS Foundation, a California-based 501(c)(3) charity dedicated to combating the aging process.
He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging. He received his BA and Ph.D. from the University of Cambridge in 1985 and 2000 respectively.
His original field was computer science, and he did research in the private sector for six years in the area of software verification before switching to biogerontology in the mid-1990s.
His research interests encompass the characterization of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging and the design of interventions to repair and/or obviate that damage.
He has developed a possibly comprehensive plan for such repair, termed Strategies for Engineered Negligible Senescence (SENS), which breaks aging down into seven major classes of damage and identifies detailed approaches to addressing each one.
A key aspect of SENS is that it can potentially extend healthy lifespan without limit, even though these repair processes will probably never be perfect, as the repair only needs to approach perfection rapidly enough to keep the overall level of damage below pathogenic levels.
Dr. de Grey has termed this required rate of improvement of repair therapies “longevity escape velocity”.
Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organizations.
Links worth a look:
SENS Foundation. Advancing Rejuvenation Biotechnologies. sens.org/
“Do You Want to Live Forever: Aubrey de Grey thinks he knows how to defeat aging. He's brilliant, but is he nuts?” Technology Review, Feb 2005. technologyreview.com/biomedicine/14147/
“Aubrey de Grey Responds.” Technology Review, Jan 2005. technologyreview.com/Infotech/14097/