Beyond automating productivity and supporting decision making, Artificial Intelligence can also be designed to help people to flourish and grow. As people across ages and stages begin to live with AI in the home, we have the opportunity to develop autonomous machines that can support a diversity people as emotionally intelligent and capable allies. This is particularly poignant as societies struggle to meet the growing demands of aging, chronic disease management, mood disorders, and lifelong learning. This gives rise to important challenges and opportunities for how to design, deploy and evaluate the long-term impact of socially and emotionally intelligent machines in the real world to help people learn, thrive and emotionally connect. This requires a tightly interwoven approach at the intersection of design, human social psychology, ethics, and AI. We have the opportunity to develop AI that places human growth and wellbeing at the center to benefit everyone in personally meaningful and uplifting ways.