The application of engineering mechanics to biological systems is an integral part of any Biomedical Engineering (BME) curriculum. This general application is usually termed “Biomechanics”, and consists of the analysis of bodies at rest (engineering “statics” and “strengths of materials”) and bodies in motion (engineering “dynamics”). These topics are often particularly challenging to students since they rely on advanced mathematics to describe abstract concepts, such as stress, strain, and virtual coordinate systems. The LIT-redesigned BME 167 — Introduction to Engineering Biomechanics curriculum aims to strengthen student understanding of the fundamental relationships in Biomechanics through hands-on activities. A series of “take-home” lab assignments are used to reinforce the connection between physical phenomena, mathematical relationships, and abstract concepts. Students work in groups on these take-home labs to construct their own materials testing systems using low-cost sensors, Arduino microcontrollers, and everyday materials. They then use these systems to conduct experiments directly related to their traditional pencil-and-paper homework assignments. The hands-on activities introduced through the LIT-redesign aim to provide a stronger foundation in the basics of biomechanics, as well as an introduction to the essential hardware required for empirical data acquisition, enabling the students to more easily draw connections between these basics and the more complex applications in Biomedical Engineering.