In this feature length documentary, renowned botanist, explorer, and author Wade Davis, follows in the footsteps of his mentor to experience for himself the mind bending discoveries that Schultes brought to the western world. Get an insight into native ceremonies and learn the secrets of shamans and medicine men. Retrace the thrilling exploration that transferred ancient knowledge to the developed world. Finally, visit laboratories in Switzerland to explore the evolution of psychedelic substances from sacred plants to LSD. Legendary writers, musicians, and Beat poets offer insight into the counterculture and mainstream influence of botanical compounds.