Authors: Hiroaki Natsukawa , Shungo Ishino , Yosuke Onoue , Koji Kyoda , Dr Shuichi Onami , Koji Koyamada
Abstract: Genes are responsible for protein synthesis and ultimately shape us. Both genes and phenotypic characters have complex interactions. Therefore, connecting biologically different hierarchies, such as genomics and phenomics is an important approach to understand the biological mechanism. Here, we propose an explorative visualization system that enables biologists to explore interactively both the phenotypic character network and the genotypic network of the nematode Caenorhabditis elegans. These two networks are visualized in multi-view and linked based on the relationship between gene and phenotypic character investigated by RNAi technology. This tool supports biologists to narrow down the complex networks with the filtering function, the user interaction and domain knowledge, leads to discovering new findings and hypotheses in the life sciences field.