Another one from my fire R&D with Cinema 4D and the plugin TurbulenceFD.
Sim time: 5,5 minutes (GPU sim only, GTX470)
Rendertime: Not sure...less than 5 minutes certainly.
The scale of the simulation: That disc on which the explosion takes place has a radius of 10m. You can see a tiny blue figure to the right, he/she/it is 180cm high.
Hardware: As on profile page.