Kinesin subfamilies have an underlying asymmetric charge distribution.
consensus potential (where we go through all structures and map their electrostatic potentials to a fine 3D grid. Then for every gird point we asked what percentage of structures have a positive potential at this point in space?) Indicates that kinesin family members have a striking asymmetric charge distribution.
The movie shows the 80% level with a transparent surface and the 100% level with solid surface. Note the positive
potential region (blue) over the back face, particularly loop8, loop7 and alpha5, and the negative potential located near the loop before alpha3.