STXBP1 Research Roundtable 2021: Mechanisms of Disease Session

Day 2 Kickoff: Ben Prosser, PhD

Session Chair: Jacqueline Burre, PhD (starting at 3:00)

Dissecting STXBP1 disease mechanism, one molecule at a time - Frederic Meunier, PhD (starting at 7:30)

Reduced MUNC18-1 levels, synaptic proteome changes and altered network activity in STXBP1-Syndrome patient neurons - Hanna Lammertse, MSc and Annemiek van Berkel (starting at 29:41)

Multiplicative effects of a modifying gene explains phenotypic diversity in STXBP1 syndrome - Jovana Kovacevic, PhD (starting at 40:58)

Panel (starting at 53:29)