The eldest brother of the family, Catholic Priest Paul (Newman), and his doctor nephew Rocco, team up together to stop Paul's mentaly insane brother Walken (Christopher), from killing the President of the United States, Bill Clinton. Walken has been in jail for 30 years and now free, is once again running the BRONXBROTHERS family business of crime in New York with his underboss Sharky(Penn) and the corrupt Senator of New York, Mel (Gibson). Walken has a son named Junior, as his bodyguard, and a daughter named Angelina (Jolie), as his top assassin. Her soon ex-husband, Johnny (Depp), a gypsy heroin addict, has taken incriminating photo's of Walken's business partner Senator George Bush, in an attempt to blackmail him to get Angelina back. Sadly the cities of New York and Washington D.C. burn from a terroist firebomb masterminded by Walken. Ever-sweet Mary (Rocco's loving wife) watches the terrible tragedy on T.V. from home in upstate NY.