Cherokee is a town in Swain County, North Carolina, USA, within the Qualla Boundary land trust. It is located in the Oconaluftee River Valley, near the intersection of U.S. Route 19 and U.S. Route 441 within western North Carolina.
Cherokee is the headquarters for the Eastern Band of Cherokee Indians.
Eastern Cherokee history, culture, and crafts are portrayed in the historical drama Unto These Hills, presented annually during the tourist season. In is also home to three roadside attractions with zoos: Cherokee Bear Zoo, Chief Saunooke Bear Park, and Santa’s Land. Retired game show host and animal rights activist Bob Barker has called for the Black Bear zoos at these attractions to be closed, prompted by the experiences he learned of from the family of Rep. Bill Young of Florida.