Presidential Symposium
Learning and Memory: Molecules to Mind

Neural Circuits for the Formation, Expression, and Inhibition of Fear
Michael Fanselow
University of California, Los Angeles
Survival critically depends on the rapid learning of fear and the later expression of fear proportional to the degree of threat. Once formed, fear memories are usually permanently maintained, but over time their characteristics can change such that they incubate and overgeneralize. By imaging activity-regulated gene expression, direct brain manipulations, and behavioral testing, I will examine how these processes arise from interactions among the amygdala, hippocampus, and prefrontal cortex.

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