Dr. Elena Cattaneo made this presentation at the sixth World Congress on Huntington's Disease, Rio de Janeiro, Brazil, September 15, 2013. Professor Cattaneo is Director of the Laboratory of Stem Cell Biology and Pharmacology of Neurodegenerative Diseases at the Department of Pharmacological Sciences, as well as a co-founder and first appointed Director of UniStem, the Centre for Stem Cell Research of the University of Milano, Italy. The main research theme of her lab is neural stem cells, and the molecular pathophysiology of Huntington’s disease. Funders of Prof. Cattaneo's lab include the Huntington's Disease Society of America (HDSA), Hereditary Disease Foundation, High Q Foundation, the European Union (through EuroStemCell), NeuroStemcell, ESTOOLS, NeuroNE, STEM-HD and Stem-stroke projects, Fondazione Cariplo, and Telethon Italy. Prof. Cattaneo served as a coalition investigator for HDSA, and she is a member of the board of directors of several European consortia (including EuroStemCell and NeuroNE) and the scientific advisory board of the Hereditary Disease Foundation and of the Euro-HD Network. Prof. Cattaneo's studies on neural stem cells and Huntington's disease brought her the “Le Scienze” Price for Medicine and a Gold Medal from the President of the Italian Republic in 2001. In 2005 she was awarded the Marisa Bellisario and Chiara D’Onofrio prizes, in 2006 was nominated Cavaliere Ufficiale (Knight) of the Italian Republic, and in 2013 was appointed senator for life by Italy's president, Giorgio Napolitano. Prof. Cattaneo has published 105 papers in peer-reviewed journals, has given more than 200 invited lectures, and is very active in organizing professional development and outreach events for both the scientific community and lay public.