2011 Joint AAPM/COMP Meeting
Dr Dimitris Visvikis, INSERM, Brest, 29609, FRANCE
For more information about the American Association of Physicists in Medicine, visit aapm.org/

The use of PET data into the treatment planning process has been the focus of intense
development over the past few years. The availability of multi-modality devices such as
PET/CT has clearly intensified the interest on the use of PET information for treatment
planning and associated research and development. The potential of such functional data
includes the identification of tumour specific physiological processes and associated 3D
functional volumes which in turn hold the potential of personalized treatment planning.
However, there are numerous issues associated with the use of PET derived information in
treatment planning, starting from the image acquisition protocols, the tracer or combination of
tracers to be used, the fusion of PET and planning CT images, the accurate extraction of 3D
functional volumes from the reconstructed PET images, and finally the different scenarios for
the incorporation of the functional information in dose planning and delivery. This paper will
review, primarily from a technological point of view, the current status of the integration of
PET/CT data into the treatment process, discussing current successes and failures, as well as
reflecting on the future. The use of PET data must be based upon a clear understanding of the
interpretation and limitations of the functional signal. Subsequently consideration will be
given to the requirements of PET/CT data acquisition and subsequent image processing
accounting for technological limitations associated with current state of the art PET/CT
devices. Approaches for the definition of functional/tumour volumes and the mechanisms
available to measure and include physiological motion into the imaging process will be also
reviewed. Finally the impact of these technological issues on current protocols for the
implementation of functional data in the treatment planning process will be presented.

Learning objectives:

Understand the main incentives behind the use of PET in treatment planning.

Understand the issues associated with the use of PET information in treatment planning.

Understand the current status and potential future developments for the optimal integration of
PET functional data in treatment planning

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