Celebrated by the 2012 Nobel Prize in Medicine, a type of cell known as an "induced pluripotent stem cell" or "iPS cell" has important implications for the emerging field of biomedical technology. In this video, Canadian scientist Dr. Mick Bhatia explains how iPS cells are created and how they can be used to create new therapies for human disease.
What are stem cells? - stemcellnetwork.ca/index.php?page=what-are-stem-cells
Induced pluripotent stem cells - en.wikipedia.org/wiki/Induced_pluripotent_stem_cell
Dr. Mick Bhatia - sccri.mcmaster.ca/bhatia_mick.html
Most of the cells in our bodies are not stem cells.
For example, blood and skin cells are specialized. They perform specific functions in the body and they got this way through a process known as differentiation that is normally not reversible.
However, if some adult cell types are taken, grown in plastic dishes and given specific genetic instructions, over time, some of these cells will reverse from their differentiated state and develop the ability to re-differentiate into any cell type in the adult. This newfound ability is known as pluripotency, and it is why these cells are known as induced pluripotent stem cells, or iPS cells.
The creation of iPS cells from individual patients may one day allow us to develop replacement tissues that are a perfect match to the patient. In addition, the creation of iPS cells from patients with specific diseases will allow scientists to develop new drugs to treat a wide variety of disorders.
Narration by: Dr. Mick Bhatia
Written & Directed by: Ben Paylor & Mike Long
Produced by: Infoshots - infoshots.ca
Animation by: David Murawsky - davidmurawsky.com/
Sound by: James Wallace - imdb.com/name/nm0908691/