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Hydroxychloroquine has been studied for the treatment and prevention virus.

A drugs which is a less toxic derivative of chloroquine (CQ), has been shown to be effective in inhibiting infection in vitro. At least one non-randomized clinical trial has been performed in Europe. Patients received 10 days of HCQ daily and underwent daily testing of viral loads from nasopharyngeal swabs.

Malaria

Indicated for prophylaxis of malaria in geographic areas where chloroquine resistance is not reported400 mg (310 mg base) PO weekly, starting 2 weeks before exposure and continued for 4 weeks after departure from endemic area ORWeight-based dosing: 6.5 mg/kg (5 mg/kg base) PO once weekly, not to exceed 400 mg (310 mg base), starting 2 weeks before exposure and continued for 4 weeks after leaving the endemic areа.