Watch Dr. Helen Mayberg's passionate, enlightening talk about deep brain stimulation as a new experimental therapy for treatment-resistant depression. Dr. Mayberg pioneered this technique, which delivers small bursts of electrical current to a patient's subcallosal cingulate white matter via a surgically implanted electrode. Many patients who have received this technique have reported tremendous weight lifting from their spirits--one patient likened it to "the first crocus coming up in the spring," Dr. Mayberg reports. This talk looks at the theory and data behind why DBS was first piloted for depression, and examines what is being discovered in long-term clinical and imaging studies of DBS patients. Recorded at the Staglin Music Festival for Mental Health 2009.