An Interview with Dr. Timothy Newman, the Director, ASU Center for Biological Physics. Newman has developed the Subcellular Element Model (SEM), which is an algorithm designed to simulate large multicellular systems, with special attention to the three-dimensional nature of cell deformations and biomechanics. A new phase of SEM development within this Core will be to couple (primarily physical) cell behavior with simple models of intracellular gene expression and cell-cell signaling. The SEM was originally designed to model cell movement patterns in developing embryonic systems. Cancer tumors lack the organization of embryos, but share the feature of emergent properties arising from a large number of strongly interacting cells. SEM is a core for the Center for the Convergence of Physical Science and Cancer Biology.