Although Ortiz was the fighter moving up in weight, on fight night he was 161 on HBO's unofficial scale while Berto was 156. At Friday's weigh in, Ortiz weighed in at the contracted catchweight of 146 pounds, while Berto weighed 145.5. Ortiz outpointed Andre Berto to take Berto’s welterweight title.
Ortiz took the fight to Berto (27-1, 21 KOs) from the beginning and almost never let up. Berto fired back throughout the fight but wasn't able to fully cope with the challenger’s relentless pressure and hard, accurate punches. The knockdowns started almost immediately, Ortiz sending Berto down to one knee—and hurting him—with a combination in the first round. Berto returned the favor in the second with a right to the chin, forcing Ortiz to touch the canvas with his glove. Ortiz won the next three rounds by continuing to fire punches, many of which landed. Again, Berto punched back but couldn’t keep pace. In the sixth round, Ortiz dropped his left hand and Berto landed a huge right about two minutes into the round, putting Ortiz on his back. Ortiz survived and put Berto down with a short left with a few seconds remaining in the round. Ortiz controlled the remainder of the fight as he had most of the first six rounds, pounding Berto inside with hard shots to the body and head as Berto failed to keep up.