What is Matrilyzer?
Matrilyzer is a home monitoring device for measurement of collagenase activity from a blood finger-stick.
What are collagenases and how are they related to cancer?
Collagenases are enzymes, which break down the extracellular matrix (ECM) holding cells together in healthy tissues. Collagenase-assisted ECM breakdown and remodeling facilitates cancer escape from the primary site, invasion of distant tissues, and formation of distant metastases.
What is the meaning of Matrilyzer readings?
Absolute level of collagenase activity varies from person to person, and is influenced by other process such as wound healing or other tissue damage. With regular monitoring, however, Matrilyzer may be able to detect consistent trend elevation, suggesting invasive metastatic process.
What do I need to perform a Matrilyzer test?
Upon enrollment in our pilot program, you will receive one Matrilyzer device and fifty disposable tests. Matrilyzer is an attachment for iPhone/iPod/iPod, so you will need one of those. The Matrilyzer app is available for free from iTunes. For getting blood through finger-stick we recommend off-the-shelf lancing devices that are available for glucose testing.