1. At Boreal, we develop tools that enable non-invasive detection and monitoring of tumor mutation profiles.

    Today, genomic profiling of cancer is increasingly important for cancer research and development of targeted therapies. As more of these targeted therapies are developed and approved, recurrent genomic profiling of tumors will be essential for clinical research and cancer treatment. New approaches are required as current technologies for tumor mutation detection are invasive and not well suited for repeated tumor profiling. We are overcoming this challenge by developing breakthrough technologies for non-invasive detection of cancer mutations.

    Our OnTarget™ platform, available as both an instrument or research service, allows researchers to detect customized panels of over 100 mutations from plasma or tissue.

    We are a team of specialists in cancer genomics, molecular biology, engineering and physics with a passion to develop technology that impacts cancer research and treatment. We are confident that our technology will enable the first practical method for non-invasive tumor profiling. We invite you to join us in our quest to help cancer researchers and clinicians transform the detection and monitoring of cancer.

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  2. Webinar presented by Dr. Andre Marziali, Chief Scientific Officer, Boreal Genomics on November 15, 2012

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  3. Webinar from June 11, 2013 presented by Dr. Andre Marziali, Chief Scientific Officer

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  4. Boreal Genomics presents a webinar on the Aurora nucleic acid system and SCODA electrophoresis.

    List of suggested reading and references:

    Pel et al. 2009. Nonlinear electrophoretic response yields a unique parameter for separation of biomolecules. PNAS 106(35):14796-801
    - https://www.ncbi.nlm.nih.gov/pubmed/19706437

    Engel et al. 2012. Nonlinear electrophoresis for purification of soil DNA for metagenomics. J Microbiol Methods. 88(1):35-40
    - https://www.ncbi.nlm.nih.gov/pubmed/22056233

    Schmedes et al. 2013. Effective removal of co-purified inhibitors from extracted DNA samples using synchronous coefficient of drag alteration (SCODA) technology. Int J Legal Med. 127(4):749-55
    - https://www.ncbi.nlm.nih.gov/pubmed/23254459

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Boreal Genomics

Boreal Genomics

Boreal Genomics is a biotechnology company that develops tools for non-invasive detection and monitoring of tumor mutations. By profiling tumor mutations in a patient's blood plasma, Boreal enables cancer researchers to continuously adjust treatment in…


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Boreal Genomics is a biotechnology company that develops tools for non-invasive detection and monitoring of tumor mutations. By profiling tumor mutations in a patient's blood plasma, Boreal enables cancer researchers to continuously adjust treatment in response to tumor load and evolution.

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