1. Dr. Agus proposes a new “systemic” model of health that will dramatically change not only how we take care of ourselves, but also how we spur the next generation of treatments and, in some instances, cures. It’s like that old saying of having to go to war in order to understand peace. His war on cancer in particular has given him a rare and unique vantage point that he has used to develop this different way of honoring the body’s preferred way of life. His ultimate goal is to teach people how to stave off illness and save their own lives through the tactical strategies of personalized medicine and practical prescriptions that are tailored to their specific needs and bodies.

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  3. The story of cancer begins approximately 1 billion years ago, with the rise of multicellular organisms. Before that point, there was no cancer. Afterwards, cancer was the central problem threatening the integrity of the body. Cancer has become a particular problem in developed countries. In the U.S., men have a 45% and women a 38% lifetime risk of developing cancer. Despite the enormous progress we have made in technology and medicine in the last 50 years, we have made almost no progress reducing deaths from cancer, even when we take into account changes in lifespan.

    Why is cancer such a difficult problem to solve? Because cells in tumors evolve. Tumor cells mutate a high rates and compete for space and resources like oxygen. Mutant cells that can reproduce or survive better than their competitors tend to spread in a tumor. Thus, tumors are microcosms of natural selection. By the time we detect a tumor in the clinic, it contains billions of cells carrying tens of thousands of mutations. By chance, some of those mutant cells are often resistant to the anti-cancer drugs we use. The result is temporary remission followed by relapse with a resistant tumor. Therapeutic resistance is so common that attention has recently switched to detecting cancer early in its development when it is still easy to cut out, or preventing cancer altogether.

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  4. Cancer is often diagnosed by examining a tissue and noting that the architecture of the cells and the extracellular matrix is abnormal. Individual cells seem to have lost their regular shape and become more squishy. Just how squishy an individual cancer cell may be is what Robert Ros’s team is measuring.

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  5. Nobel Prize winner Lee Hartwell talkes about cancer research for the Beyond Center
    Lee is the President and Director of the Fred Hutchison Cancer Research Center, the Executive Chairman of the Arizona-based Partnership for Personalized Medicine and
    the Director of the newly formed Center for Sustainable Health at the Biodesign Institute.

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The Center for Convergence of Physical Science and Cancer Biology at ASU

ASU Biodesign Institute Plus

Despite decades of research, cancer remains a major killer worldwide. So could progress in understanding and controlling malignancy be made by scientists from outside the established cancer research community? That fresh approach is behind a new research…


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Despite decades of research, cancer remains a major killer worldwide. So could progress in understanding and controlling malignancy be made by scientists from outside the established cancer research community? That fresh approach is behind a new research center at ASU – one of 12 Physical Sciences-Oncology Centers nationwide established by the National Institutes of Health's National Cancer Institute. This channel will host video content related to this exciting initiative.

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