Chris Enke was one of the creators of the Triple Quadrupole Mass Spectromenter in the 1970s. In this interview with Mike Grayson, Enke describes the series of events that led to this breakthrough, and what impact it has had on the field of mass spectrometry. This conversation was held at the 2014 American Society for Mass Spectrometry Conference (

00:40 "It was considered a toy"
2:30 Creation of the Triple Quadrupole Mass Spectrometer "It one of those completely serendipitous situations"
8:00 "Noise" breakthroughs with Jim Morrison and Rick Yost
12:00 "I didn't sleep very much that night ... It's a very interesting story because ... one man's noise is another man's answer"
15:00 How the concept was received
18:00 Legacy of the Triple Quad "It's the go-to instrument for quantitation"
22:00 "A giant boost" for the Triple Quad and the growth of "comprehensive analysis" for biological applications using big data
25:00 On retirement, and the drive of modern scientists to produce: "I think it's important during in my retirement to be able to choose what I want to do and when I want to do it."
30:00 Taking advantage of technological advances "I think there's some things we're missing"
33:00 "It's a nice place to be ... "


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