Pershing Square Sohn Cancer Research Alliance

  1. The Pershing Square Sohn Cancer Research Alliance was formed in 2013 through a $25 million commitment by Bill Ackman and The Pershing Square Foundation, which partnered with The Sohn Conference Foundation. The Alliance is dedicated to playing a catalytic role in accelerating cures for cancer by supporting innovative cancer research and by facilitating collaborations between academia and industry. Annually, the Alliance awards The Pershing Square Sohn Prize to young New York based scientists who are engaged in cutting-edge cancer research.
    For more information, visit psscra.org/.

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  2. Swarnali Acharyya, PhD, Columbia University Medical Center: Dr. Acharyya’s project will study the biology of metastatic progression and the systemic changes induced by these tumors. Her group will investigate how tumor factors induce muscle wasting, a debilitating condition associated with advanced cancer. Many cancer patients die from the systemic effects of their tumors and this work could lead to an alternative strategy of treating cancer that could prolong patient survival.

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  3. Adrienne Boire, MD, PhD, Memorial Sloan Kettering Cancer Center: Dr. Boire studies the spread of cancer into the spinal fluid (Leptomeningeal metastasis, “LM’). Her project will explore how cancer cells exploit immune cells in order to metastasize and spread into the spinal fluid through a structure called the choroid plexus. Unlocking the mechanisms by which cancer cells spread into the spinal fluid will reveal potential targets for therapy and a novel approach for LM treatment.

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  4. Yael David, PhD, Memorial Sloan Kettering Cancer Center: Dr. David’s research looks at how cancer cells evade damage from modifications to proteins in the cell after exposure to sugars, known as glycation. She hypothesizes that through overexpressing the gene DJ-1, these cancer cells survive and thrive in an unstable metabolic environment that would typically induce cell death.

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  5. Matthew Greenblatt, MD, PhD, Weill Cornell Medicine: Dr. Greenblatt’s research will focus on tumor growth in the bone. His lab has discovered the presence of different stem cells in the bone and how specific groups of skeletal cells participate in the ability of tumors to destroy bone. This research will establish a new paradigm for how tumors interact with bone and will lead to the development of drugs that promote the growth of cells that make the bone inhospitable for cancer growth and prevent bone destruction.

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Pershing Square Sohn Cancer Research Alliance

The Pershing Square Foundation PRO

The Pershing Square Sohn Cancer Research Alliance is dedicated to pursuing breakthroughs in curing cancer by advancing the most innovative cancer research and by facilitating collaborations between the science and business communities.

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