1. Laser rapid prototyping of bioactive materials for medical treatment

    04:13

    from Ilka Brosch / Added

    42 Plays / / 0 Comments

    Scientific video about laser rapid prototyping of bioactive materials for medical treatment. I did the animation for the Beilstein-Institut zur Förderung der Chemischen Wissenschaften. Filmed at the Center for Nanointegration Duisburg-Essen. Produced by ACAM GmbH

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    • Leaving It Up to Chance: How Cells Make Decisions

      54:55

      from Science for the Public / Added

      2 Plays / / 0 Comments

      Science for the Public 3/18/14. Jané Kondev, Professor and Chair, Dept of Physics, Brandeis University. Two cells that are genetically identical and placed in the same environment can behave in radically different ways. In this talk Dr. Kondev first describes the random nature of cellular decision making and then how this randomness is forcing us to reexamine basic ideas about cell "decisions", aspects of "life" and important health related problems like bacterial infections and cancer. Great animations!

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      • "Intimidating at first:" An inside look at a Harvard research department

        05:32

        from Harvard Medical School / Added

        489 Plays / / 0 Comments

        An intimidating environment? Perhaps. But these researchers and staff members at Harvard Medical School's Department of Biological Chemistry and Molecular Pharmacology know how to balance hard work and fun.

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        • Protein power

          02:50

          from College of Biological Sciences / Added

          236 Plays / / 0 Comments

          Casey Solomon, a biochemistry, molecular biology and biophysics graduate student in the lab of Hiroshi Matsuo, talks about his fascination with proteins and his research at the U of M's Nuclear Magnetic Resonance facility. More about Casey: www.cbs.umn.edu/explore/departments/bmbb/frontpage/solomon

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          • Cas9: The Enzyme, the DNA, and the Virus

            02:46

            from Myles Marshall / Added

            293 Plays / / 0 Comments

            An educational video short describing research on Cas9. More detailed information can be found at: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13011.html Bacteria can become infected with viruses just like us. We have a complex immune system that defends us from invading pathogens. But bacteria lack an immune system similar to our own, so how do they protect themselves from viruses? One way bacteria can defend themselves is by producing a special protein called Cas9, which can destroy viral DNA. But how does Cas9 find the viral DNA, and what prevents it from destroying the bacteria's own DNA? It turns out that bacteria can steal small snippets of viral DNA, and then store these stolen fragments in their own genomes like a library representing the complete history of viruses that the bacteria have been exposed to in the past. If a virus ever tries to come back, the bacteria make RNA copies of these DNA sequences. Cas9 then grabs the bits of RNA and uses them like a fingerprint to identify the viral invaders. DNA sequences matching the RNA occur only twice: once in the virus and once in the bacteria's library. So why doesn't Cas9 destroy them both? The secret lies in a short 3 letter DNA code called the PAM. The virus' DNA has a PAM in the right location, but the bacteria's DNA does not, so Cas9 uses the PAM to help it identify the virus. In this video, we follow Cas9 as it hunts down and destroys the viral DNA with its sidekick, the strand of RNA that is complimentary to a small portion of the virus' DNA. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9. Samuel H. Sternberg, Sy Redding, Martin Jinek, Eric C. Greene, and Jennifer A. Doudna. (n.d.) Nature.doi:10.1038/nature13011

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            • Cellulosic Ethanol: Simulation of Multicomponent Biomass System

              01:31

              from OLCF / Added

              348 Plays / / 0 Comments

              ORNL Researchers learn more about biomass recalcitrance. Visualization by Mike Matheson (ORNL). Learn more at https://www.olcf.ornl.gov/2014/01/02/boosting-bioenergy/

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              • Molecular Switch

                00:58

                from OLCF / Added

                2,622 Plays / / 0 Comments

                The flipping conformations in a pair of phenylalanine amino acids called Phe396 (blue and red molecules) act as a molecular switch essential to the signaling mechanism of an E. coli chemoreceptor. Research indicates this switch could be present in most organisms. Image credit: Davi Ortega. To learn more, visit https://www.olcf.ornl.gov/2013/12/13/researchers-recruit-titan-to-study-key-molecular-switch-that-controls-cell-behavior/

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                • Creation of elements – supernova in the lab

                  05:08

                  from Ilka Brosch / Added

                  78 Plays / / 0 Comments

                  The gold found on Earth is to a large extent the product of supernovae. Other elements are also created during these violent astrophysical explosions. Karlheinz Langanke and his colleagues at GSI carry out research into the nucleosynthesis process. Here, an important role is played by the super fragment separator; a construction made of huge magnets which acts like a sieve, filtering out the nuclei of interest from a large mixture. I did the animation for the Beilstein-Institut zur Förderung der Chemischen Wissenschaften. Filmed at the GSI Helmholtzzentrum für Schwerionenforschung. Produced by kemweb.tv

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                  • Tumor therapy – Fast ions in the fight against cancer

                    04:31

                    from Ilka Brosch / Added

                    55 Plays / / 0 Comments

                    Tumors can be treated using ion-beam radio-therapy. Ions are accelerated to precisely controlled speeds in a particle accelerator. They penetrate into the body, almost without harming healthy tissue until their energy is released in the tumor destroying the malignant cells. Robert Kaderka explains how this therapy works and how he and his colleagues at the GSI biophysics department are further developing the method. I did the animation for the Beilstein-Institut zur Förderung der Chemischen Wissenschaften. Filmed at the GSI Helmholtzzentrum für Schwerionenforschung. Produced by kemweb.tv

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                    • Enliven: Bioinformatics

                      00:59

                      from Enliven Archive / Added

                      475 Plays / / 0 Comments

                      Enliven: Bioinformatics is an Open access, peer reviewed international journal and it aims to publish different types of articles on emerging developments and supports current and upcoming research in the field of Bioinformatics. This journal also allows articles on Bioinformatics, genomics, and proteomics.

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