1. Chas Bountra: Drug Discovery


    from NDM Oxford Added 1 0 0

    Professor Chas Bountra is interested in identifying and validating target proteins for drug discovery. Successful compounds are tested in the lab, on healthy volunteers and patients. Academic research excels at defining good target proteins whereas pharmaceutical companies facilitate the transition from basic research to clinical trials, producing new therapies for patients. Professor Bountra has identified valid target proteins for drug discovery and is working on novel drug treatments for a number of chronic diseases.

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    • Conformational switch of the ryanodine receptor


      from VIB Added 68 0 0

      Every single moment our life depends on the reliable functioning of muscles. Even slight malfunction of muscles results in diseases. To be able to treat and prevent muscle associated disease we need to understand their structure and function in molecular details. Muscular contraction is initiated by release of calcium ions from sarcoplasmic reticulum, the intracellular calcium reservoirs. This process it mediated by calcium release channel, also known, as ryanodine receptor. The mechanism of the release has remained enigmatic for nearly thirty years.

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      • Eva Nogales, HHMI Investigator, University of California, Berkeley


        from Jim Keeley Added 323 0 0

        Eva Nogales talks about her approach to science and why it's good to be fearless.

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        • Information campaign on structural biology animation - Bio-NMR


          from Spronk Studio Added 368 1 0

          The animation is part of an information campaign of the Bio-NMR project (www.bio-nmr.net) to promote Structural Biology and NMR in the new EU member states.

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          • Introduction to X-ray crystallography


            from harvardbmw Added 8,060 6 2

            Courtesy of Claude Sauter http://cj.sauter.free.fr/xtal/home.html

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            • Magnet to send bio research ability ‘through the roof’


              from Brown University Added 926 0 0

              Go for a ride with a Bruker 850 nuclear magnetic resonance spectrometer as it's lowered by crane through the roof of the Structural Biology Core Facility at 70 Ship St. The humongous and powerful magnet, with a field strength of 19.97 Tesla, is a powerful new tool for molecular biology research. Find out more: http://news.brown.edu/pressreleases/2013/02/tesla

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              • Panagis Filippakopoulos: Targeting epigenetics to treat cancer


                from NDM Oxford Added 11 0 0

                Professor Panagis Filippakopoulos from the Structural Genomics Consortium explains how we can target epigenetic mechanisms to treat cancer

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                • Panel discussion on structural biology (MVA Annual Meeting 2013)


                  from Medicon Valley Alliance Added 21 0 0

                  Watch the panel discussion about structural biology from Medicon Valley Alliance's 2013 Annual Meeting. Panellists: Bjørn Walse, CEO at SARomics Biostructures AB Esko Oksanen, Instrument Scientist for Neutron Macromolecular Crystallography at ESS Lena Tagmose, Head of Department, Computational Chemistry and Structural Biology at H. Lundbeck A/S Marjolein Thunnissen, Associate Professor, Biochemistry and Structural Biology at Lund University & Scientific Coordinator for MX at MAX IV Laboratory Morten Dahl Sørensen, Senior Scientist, Chemical Research at Leo Pharma A/S

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                  • PIMS-LIMS


                    from David Aragao Added 388 1 0

                    PiMS is a Laboratory Information Management System (LIMS) designed to help you to manage Target, Construct and Experiment data through a web interface. More information can be found on its website http://www.pims-lims.org/

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                    • Revolutionary Biology Part 3: Advanced technology


                      from NDM Oxford Added 389 0 0

                      Just over a decade ago the face of British farming changed forever. A devastating outbreak of Foot and Mouth disease led to the enforced slaughter and incineration of over 10 million livestock across the country. While this mass culling halted the spread of disease in the UK, the fight against Foot and Mouth continues to this day, predominately in developing countries. Fortunately, cutting edge structural biology research is paving the way for a new vaccine, set to revolutionise farming on a global scale.

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