1. Gregory A. Otterson, MD, on Adjuvant Therapy and Immunotherapy for Lung Cancer


    from Harborside Press / Added

    91 Plays / / 0 Comments

    Gregory A. Otterson, MD, of The Ohio State University Comprehensive Cancer Center and the James Cancer Hospital and Solove Research Institute, discusses the evolution of lung cancer treatment from adjuvant chemotherapy to immunotherapy and the clinical trials underway.

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    • Melanoma Patients Benefit from New Treatments


      from Lee Memorial Health System / Added

      19 Plays / / 0 Comments

      Immunotherapy and targeted therapy - two modern day buzzwords in the treatment of cancer. What used to seem hypothetical is now reality. Advanced melanoma is one success story. “For years we used Interferon which is a broad immune system stimulator. Unfortunately it does have side effect. As more was discovered about melanomas we started to understand where the immune system was not functioning properly,” says oncologist Frank Rodriguez, M.D. Dr. Rodriguez is on medical staff of Lee Memorial Health System. By understanding how particular cancers replicate, researchers developed ways to hinder the process, which is the fundamental of immunotherapy. “Yervoy is something that we use to accelerate the immune function. In accelerating the immune function it identifies and destroys these melanoma cells,” Dr. Rodriguez says. Combating cancer with medication often takes several different treatments to out-smart the cells and exploit their duplication. The FDA recently approved a second drug that targets melanoma, setting up a dynamic duo. “Melanoma cells are able to disguise themselves or camouflage themselves within our bodies. And what Keytruda does is it removes that camouflage. It makes them visible to the immune system,” says Dr. Rodriguez. By exposing the cancer cells, the immunotherapy drugs can mount their attack. This powerful combo is having significant results. “Which is really an exciting thing, not just because we have a new drug, but because it opens the door to a whole new way of targeting these cells.” The future is coming to fruition- researchers are evaluating these drugs for use in lung cancer and others that replicate in the same manner. View More Health Matters video segments at leememorial.org/healthmatters/ Lee Memorial Health System in Fort Myers, FL is the largest network of medical care facilities in Southwest Florida and is highly respected for its expertise, innovation and quality of care. For nearly a century, we’ve been providing our community with everything from primary care treatment to highly specialized care services and robotic assisted surgeries. Visit leememorial.org

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      • Anthony J. Olszanski, RPh, MD, on Immunotherapy and Melanoma


        from Harborside Press / Added

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        Anthony J. Olszanski, RPh, MD, of the Fox Chase Cancer Center, discusses the advances in immunotherapy generally and for melanoma in particular.

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        • Why Cancer Made Me a Better Thoracic Oncologist


          from Patient Power / Added

          604 Plays / / 0 Comments

          Thoracic oncologist, Dr. David P. Carbone, speaks candidly about his experience with cancer and how having cancer shifted his family dynamics drastically. Married with four children, Dr. Carbone self-diagnosed his large b-cell lymphoma and received a partial lobectomy. With the cure-rate between 30%-50% at the time, his optimism was at an all-time low. Dr. Carbone shares how revealing the news to his then wife resulted in her departure of the marriage, leaving him a single parent of four young children. Listen as Dr. Carbone explains why having cancer has given him a new appreciation for life along with newfound empathy and perspective for his patients.

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          • 91. Ilan Kirsch- Immunosequencing in the Service of Immunotherapy (Track 2)


            from PMWC Intl / Added

            34 Plays / / 0 Comments

            Ilan Kirsch, M.D., SVP, Translational Medicine, Adaptive Biotechnologies Recent advances in our understanding of the adaptive immune system have enabled development of many promising new drugs, vaccines and procedures that harness the body’s own defenses to combat cancer. As these novel immunotherapies establish an increasingly important role in cancer management, there is a corresponding need to develop effective clinical diagnostics that can characterize the immune response in a given patient and in that patient’s tumor. Immunosequencing has dramatically enhanced our understanding of this response by enabling highly sensitive and accurate quantification of the systemic immune receptor repertoire and the repertoire of tumor infiltrating lymphocytes (TILs), an approach that has shown promise in both research and clinical contexts. As exemplified by selected studies, TIL enumeration and quantification has the potential to serve as a biomarker that can inform prognosis and staging, predict response to treatment, monitor treatment effectiveness, and detect early signs of toxicity. For more information go to PMWCintl.com

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            • T-Cell CAR Therapy for Pediatric Solid Tumors: Are we there yet?


              from Solving Kids' Cancer / Added

              38 Plays / / 0 Comments

              Recently, T-cell CAR immunotherapy has resulted in dramatic complete remissions in early phase clinical trials for children with ALL, and adults with CLL. These results have opened the door for immune cell therapy to treat and potentially cure aggressive and deadly cancers, and may be applied to other cancers like neuroblastoma, sarcomas and brain tumors. Can we look forward to the same success in pediatric solid tumors and brain tumors? In which pediatric cancer types are T-cell CARs closest to the clinic? Dr. Stephan Grupp, a pioneering immunotherapy researcher for pediatric cancer, will discuss the current state of progress and future opportunities using T-cell CARs for pediatric solid tumors.

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              • William T. Gradishar, MD, and Edith A. Perez, MD, on Highlights of the BOLERO-1 and SOFT Trials


                from Harborside Press / Added

                138 Plays / / 0 Comments

                William T. Gradishar, MD, of Northwestern University, and Edith A. Perez, MD, of the Mayo Clinic Cancer Center, discuss immunotherapy and highlights of results from the BOLERO-1 and SOFT trials.

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                • Immunotherapy principles | facingallergies.com


                  from facing allergies / Added

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                  http://www.facingallergies.com/what-solutions/allergen-immunotherapy-desensitisation/ Allergen immunotherapy works the same way as vaccination : Administrating the allergen substance, you make the body used to it which reduces the symptoms. You can also avert asthma since it also acts on its causes

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                  • Enumeral - The Power of Human(TM)


                    from MacBioCom / Added

                    Enumeral is discovering and developing novel antibody immunotherapies that help the immune system attack diseased cells. We believe human-derived knowledge will better predict which antibody drug candidates are most likely to be effective in a targeted group of patients, with the goals of reducing side effects and accelerating the drug discovery and development process.

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                    • How to get healed thanks to allergen immunotherapy | facingallergies.com


                      from facing allergies / Added

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                      http://www.facingallergies.com/what-solutions/allergen-immunotherapy-desensitisation/ This video tells you how to use immunotherapy to get over your allergy issues. It will let you know about age to start your therapy, the methods of administration and everything you need to know about starting desensitization

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