1. Working with Your Doctor to Choose a CLL Treatment Path

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    With many therapy options to consider, how can patients best discuss their CLL treatment options with their doctor? A CLL expert from Seattle Cancer Care Alliance, Dr. David Maloney, discusses his approach to determining when to treat and what factors—including age and pre-existing conditions—he considers when deciding on a treatment plan with a patient.

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    • Long-Term CLL Treatment Planning

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      With more CLL treatments recently approved, and others in clinical trials, how should patients collaborate with their doctors to get the best therapy now and in the future? A leading researcher and member of the Fred Hutchinson Cancer Research Center in Seattle, Dr. David Maloney, discusses recently approved and promising CLL therapies and explains his advice for approaching treatment in the long term.

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      • A New Oral CLL and SLL Treatment: What Could It Mean for Patients?

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        The Food and Drug Administration (FDA) recently approved idelalisib (Zydelig), a new oral inhibitor therapy to treat CLL and SLL. Patients now have another option that may spare them the need for chemotherapy and its associated side effects. A leading researcher in the field from Fred Hutchinson Cancer Research, Dr. John Pagel, shares his perspective on the significance of this new CLL treatment and what it could mean for patients.

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        • CLL Clinical Trials at the NIH

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          The National Institutes of Health (NIH) conducts clinical trials in a number of cancers, including CLL. At ASCO 2014, patient advocate Dr. Brian Koffman visited with NIH researcher Dr. Mohammed Farooqui to discuss CLL trials currently underway at the NIH, including research into the progression of the disease, BTK inhibitors and chemotherapy combinations.

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          • The Emerging Goals of CLL Treatment

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            As more information is released about new and emerging oral inhibitor CLL treatments, how are the goals of therapy evolving? What is being revealed about response rates and the potential for drug resistance? CLL advocate Dr. Brian Koffman visited with Dr. Mohammed Farooqui, from the National Heart Lung and Blood Institute, at ASCO 2014 in Chicago to discuss recent and developing research and its potential effect on patients.

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            • Understanding the Link Between Genetics and CLL Drug Resistance

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              Chronic lymphocytic leukemia (CLL) experts continue to research the potential for a patient to become resistant to new and developing inhibitor CLL treatments. Dr. Richard Furman, a leading CLL researcher, explores recent study results that show a link between genetics and resistance. Dr. Furman discusses how this new research could help to improve early detection and lead to combination treatment approaches to help overcome resistance.

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              • Hitting a CLL Treatment "Home Run"

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                As more chronic lymphocytic leukemia CLL treatments are approved, with many more in development, are researchers closer to hitting a "home run" in treating the disease? Patient advocate Dr. Brian Koffman met with CLL expert Dr. Thomas Kipps at ASCO 2014 to explore emerging therapies and the goal for patients to achieve deep remission.

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                • Update on Oral CLL Therapies

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                  What are Phase III trial results of oral chronic lymphocytic leukemia, CLL, medications revealing about their efficacy, safety and side effects? Dr. Brian Koffman met with Dr. Richard Furman, a CLL expert from Weill Cornell Medical College, at ASCO 2014 to discuss trial results and explore what the information could mean for people with CLL.

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                  • CLL Side Effects and Symptoms: When to Call the Doctor

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                    From treatment side effects to a fever from the common cold, many chronic lymphocytic leukemia (CLL) patients want to know when they should call their doctor or nurse. An advanced registered nurse practitioner at Moffitt Cancer Center, Lisa Nozden explains what she advises patients to consider.

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                    • Staying Consistent with Oral CLL Treatment

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                      Now that an oral medication has been approved for chronic lymphocytic leukemia (CLL), patients are tasked with a new responsibility: staying on schedule with their medications, in their own home. An advanced registered nurse practitioner at Moffitt Cancer Center, Lisa Nodzon, shares her advice for staying consistent with at-home treatment to help ensure optimal results.

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