1. An Introduction to the Physics, Techniques and Radionuclides in the Intravascular Brachytherapy for the Treatment of Restenosis

    54:35

    from AAPM Added 70 0 0

    An Introduction to the Physics, Techniques and Radionuclides in the Intravascular Brachytherapy for the Treatment of Restenosis Ravinder Nath PhD Yale University Ning J Yue PhD Yale University [00:00:00] Introduction to Restenosis, Techniques, and Radionuclides [00:00:40] Restenosis [00:03:16] Artery Wall Injury Model after Angio[lasty [00:03:41] Three Causes of Restenosis [00:03:51] Restenosis [00:04:39] Stents Don't Fix the Problem ... Restenosis Still Exists [00:05:09] The Problem [00:05:24] Diagram - Restenosis [00:05:30] Animal Trails with Novoste System Post PTCA [00:06:18] Animal Trails with Novoste System Post Stent [00:06:38] Radiation is Designed to Overcome Restenosis Present with Existing Therapies [00:07:33] Intravascular Brachytherapy Systems Under Development [00:08:07] Cordis CHECKMATE System [00:08:39] Treatment zone with margins [00:09:07] SCRIPPS-I [00:09:32] SCRIPPS-I - Major Adverse Cardiac Events [00:10:03] SCRIPPS-I - Saftely & Effectiveness 6-Month Data [00:10:43] GAMMA-I [00:11:00] GAMMA-I - Major Adverse Cardiac Events [00:11:15] GAMMA-I - Safetu & Effectiveness 9-Month Data [00:11:22] The Beta-Cath System [00:11:48] Start Trial 240 Day Event Free Survival - MACE [00:12:19] Edge Effect [00:13:32] Start 8 Month Angiographic QCA Analysis [00:14:06] Start 8 Month Angiographic QCA Analysis [00:15:21] Geometric Miss [00:16:02] GAMMA I & Start [00:17:53] Restenosis Problem [00:18:40] Dosimetric Requirements for IVB [00:19:45] Therapeutic Window [00:20:25] Rationale of Dosimetry Evaluation [00:21:35] Slide Unavailable [00:27:03] 30 mm long linear source - Centered Source [00:30:11] 30 mm long linear source - Off-centered to the right [00:31:25] 30 mm long linear source - Off centered to the left [00:32:42] Depth Dose Comparison [00:33:36] Ir-192 Versus P-32 Centered in the lumen 14 Gy at 2 mm [00:33:55] Radial Dose Gradient: Conclusions [00:34:19] Dose Perturbations by High Atomic Number Materials in Intravascular Brachytherapy [00:35:01] Mechanism of Dose Enhancement at Interfaces [00:36:54] Dose Ratio for 60 keV Photons [00:38:13] Dose Enhancement Factors for Stainless Steel [00:38:46] Dose Enhancement Distance for Stainless Steel [00:39:00] Dependence of dose enhancement on atomic number [00:39:48] Dependence of dose enhancement on atomic number and photon energy [00:40:51] Interface Dosimetry Effects: Conclusions [00:41:27] Interface Dosimetry Effects: Conclusions - The dose enhancement... [00:42:05] Shielding Effects of Metallic Encapsulations and Radiographic Contrast agents for Catheter-based Intravascular Brachytherapy [00:42:38] Dose Rate x r2 for 125I [00:43:43] Dose Rate x r2 for 192Ir [00:43:59] Shielding Correction Factors for 0.1 mm stainless steel: Photons [00:44:52] Shielding Effects Photons [00:45:23] Slide Unavailable [00:47:10] Penetration Depth Reduction: Betas [00:47:31] Shielding Effect Beta Particles [00:47:55] Shielding Effects og High Z Materials: Conclusion [00:48:22] Shielding Effects og High Z Materials: Conclusion - For betas... [00:48:50] Dose Planning Issues to Be Further Examined

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    • Quality Management for Intravascular Brachytherapy

      43:33

      from AAPM Added 26 0 0

      Quality Management for Intravascular Brachytherapy Bruce R Thomadsen PhD University of Wisconsin 2001 AAPM / RSNA [00:00:00] Quality Management in Intravascular Brachytherapy [00:00:32] Learning Objectives [00:00:57] What is Quality? [00:01:47] Quality Management [00:02:03] Quality Assurance [00:02:38] Quality Control [00:03:03] QA or QC? [00:03:14] Organizational Difference between QA and QC [00:04:16] Example: Calculation Error Fault Tree [00:05:02] Example: Calculation Error Tree with QM [00:05:28] Comparison of QA and QC [00:06:01] Errors [00:07:19] Error Reduction [00:07:50] Establishing A QM Program [00:08:51] Quality Management in Brachytherapy [00:09:12] IVB Fault Tree - Wrong Site [00:10:03] IVB Fault Tree - Wrong Dose [00:10:31] Delivering the Right Dose [00:10:56] Source Strength Assay [00:12:07] Source Strength Assay - Whose assay to use... [00:13:56] Source Strength QA [00:14:23] Source Uniformity [00:14:47] Source Uniformity QA [00:15:07] Autoradiograph/radiograph of a BetaCath Source Train using Kodak XV Film [00:15:51] Autoradiograph of a BetaCath Source Train using Kodak XV Film, Adjusted in Photoshop [00:17:38] Dose algorithms to give dose distributions and dose rate [00:19:01] Treatment Prescription [00:20:21] Treatment Prescription(2) [00:21:31] Treatment Prescription(3) [00:22:24] Treatment Prescription QC (1) [00:23:09] Treatment Prescription QC (2) [00:23:49] Treatment Duration Determination QC (1) [00:24:09] Treatment Duration Determination QC (2) [00:24:49] Treatment Duration [00:25:21] Treatment Duration QC [00:26:16] Treatment Duration QC - One person timing should ... [00:27:10] Timer QA [00:27:54] Delivering the Dose to the Correct Location [00:28:21] Positioning the Catheter in the Correct Location (QC) [00:29:06] Positioning the Source Correctly in the Catheters (1): QC [00:29:45] Positioning the Source Correctly in the Catheters (2): QA [00:30:18] Positioning the Sources Correctly in the Catheters (3): QA [00:30:42] Junctioning [00:32:36] Delivering the treatment Safely [00:33:03] Treatment Catheter Integrity and Patency, and Source Drive QA (1) [00:34:03] Treatment Catheter Integrity and Patency, and Source Drive QA QA (2) [00:35:19] Treatment Catheter Integrity and Patency, and Source Drive QA (3) [00:35:48] Treatment Catheter Integrity and Patency, and Source Drive QA (4) [00:36:33] Treatment Catheter Integrity and Patency, and Source Drive QA (5a) [00:36:53] Treatment Catheter Integrity and Patency, and Source Drive QA (5b) [00:38:01] Treatment Catheter Patency QA [00:38:34] Preparation for Retrieval [00:39:12] Verification of Source Recovery [00:39:56] HDR IVB Unit QA (1) Catheter Connection Interlock [00:40:35] HDR IVB Unit QA (2) Emergency Interrupt Operation [00:40:44] HDR IVB Unit QA (3) Treatment Interrupt Operation [00:40:55] HDR IVB Unit (4) Timer Operation (1): Preferred [00:42:08] HDR IVB Unit QA (4) Timer Operation (2): Alternative [00:42:28] HDR IVB Unit QA (5) Indicator Lights [00:42:47] Summary for IVB QM

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      • Radioactive Materials Licensure and Clinical Review Boards for IVB

        40:34

        from AAPM Added 12 0 0

        Radioactive Materials Licensure and Clinical Review Boards for IVB Mr. Michael Bohan B.Sc. I am making a presentation today on how to get your intravascular brachytherapy protocol up and running, and today we're going to be talking about the things that need to be addressed to get your radioactive materials license and your clinical review boards set to get an IVB program up and running. Full transcript available at : http://www.aapm.org/meetings/virtual_library/IVB/6257/transcript.html [00:00:00] Radioactive Materials Licensure and Clinical Review Boards for IVB [00:00:24] Regulatory Agencies [00:01:48] Regulatory Agencies (Cont) [00:03:09] 45CFR46 - Protection of Human Subjects [00:04:07] Purpose of the IRB [00:05:32] Institutional Review Boards [00:07:14] IRBs - Continued [00:07:54] Criteria for IRB Approval of Research [00:10:47] Criteria for IRB Approval of Research (continued) [00:11:38] Informed consent [00:12:10] Informed consent - For research involving more that... [00:12:57] Informed consent - A statement that participation is voluntary... [00:13:18] IRB Application Process [00:13:46] IRB Application Contents [00:16:02] IRB Application (Cont.) [00:17:50] IRB Application (Cont.) - Copy of Proposed Informed Consent Form [00:20:32] Protocols Involving Radioisotopes [00:22:13] Radiation Safety Approval [00:24:02] NRC and Agreement States [00:24:34] NRC License Types [00:25:33] NRC Broad Scope License [00:27:50] NRC License Types (cont.) [00:30:39] NRC Specific Scope License [00:31:09] Licensing Authority [00:31:52] Licensing Authority (cont.) [00:34:14] Licensing Authority (cont.) - Sealed sources must be tested for encapsulation before listed as a... [00:35:31] Licensing Authority (cont.) - IVB sources must be listed... [00:36:09] Licensing Authority (cont.) - Usually the Radiation Safety Officer... [00:38:19] Applying for RSC Approval [00:38:48] Applying for RSC Approval (cont.) [00:39:46] Additional References

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        • Improving Ultrasound Report Turnaround Time (Quality Project at RSNA 2010)

          01:05

          from Muhammad Kashif Mirza Added 21 0 0

          Improving Ultrasound Report Turnaround Time by Using RSNA-based Reporting Templates and Radiologist-based Examination with Speech Recognition System RSNA 2010 Project details: Exhibit Space Number: LL-QSE3046-SUB Exhibit Type: Quality Storyboard CME Day/Start-End: 11/27/11 1:00 PM – 11/27/11 1:30 PM Author(s): M. Kashif Mirza, MBBS; Syed Sohail, BEng, MBA; Zafar Sajjad, MBBS; Mohammad Yusuf, BEng; Nida Husain More details regarding media coverage in conference: http://kashifmirza2.atwebpages.com/wordpress/2010/12/06/rsna-2010-quality-story-board-gets-media-coverage/

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          • Everything you should know to improve your MRIs in less than 2 minutes

            01:53

            from MRIaudio Added 31 0 0

            How to: 1. Make technologists more efficient and effective 2. Patients more calm and comfortable 3. Imaging centers more profitable and marketable

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            • Medify RSNA 2013

              00:52

              from Medify Added 56 0 0

              3D-based virtual product showcases for Philips Healthcare "Transforming care, together" is a key strategic objective for Philips Healthcare, as iterated by CEO Deborah DiSanzo at several recent public events. Combining this with innovative 3D technology enables a completely new way to provide in-depth product exploration. The RSNA 2013 event in Chicago is used as the launch pad to transform the way Philips Healthcare products are being showcased. We were selected to create all product experiences based on its unique production pipeline of 3D assets. In using the master asset approach, Philips is able to deliver convincing and highly interactive experiences across all touch points. For INDG / Medify this project is one of the first milestones in a set of new client assignments since opening our New York office earlier in the year. It solidifies our base of operations in the US and readies for further growth in 2014. Medify, an INDG Company

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              • Philips Healthcare - RSNA 2013 Virtual product Showcase

                00:47

                from INDG Added 867 6 0

                Please visit: http://www.indg.com/ 3D-based virtual product showcases for Philips Healthcare “Transforming care, together” is a key strategic objective for Philips Healthcare, as iterated by CEO Deborah DiSanzo at several recent public events. Combining this with innovative 3D technology enables a completely new way to provide in-depth product exploration. The RSNA 2013 event in Chicago is used as the launch pad to transform the way Philips Healthcare products are being showcased. INDG was selected to create all product experiences based on its unique production pipeline of 3D assets. In using the INDG master asset approach (more here), Philips is able to deliver convincing and highly interactive experiences across all touch points. For INDG this project is one of the first milestones in a set of new client assignments since opening our New York office earlier in the year. It solidifies our base of operations in the US and readies INDG for further growth in 2014.

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                • Radiation Therapy

                  02:32

                  from Amy McWhirter Added

                  American Association of Physicists in Medicine, AAPM. Amy McWhirter as Trade Show and Medical Presenter for Elekta's Versa HD radiation therapy system.

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