1. Introduction to X-ray crystallography


    from harvardbmw Added 9,374 7 1

    Courtesy of Claude Sauter http://cj.sauter.free.fr/xtal/home.html

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    • VA. Structure of a Chaperone-Usher Pilus Reveals the Molecular Basis of Rod Uncoiling


      from In Motion Science Added 1 0 0

      ARTICLE Authors: Manuela K. Hospenthal, Adam Redzej, Karen Dodson, Marta Ukleja, Brandon Frenz, Catarina Rodrigues, Scott J. Hultgren, Frank DiMaio, Edward H. Egelman, Gabriel Waksman. Published:…

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      • Stefan Knapp: Development of chemical probes


        from NDM Oxford Added 7 0 0

        Kinases and phosphatases control a large number of cellular processes such as metabolism and cell communication; as a result they make very attractive drug targets. Professor Stefan Knapp works to…

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        • Panel discussion on structural biology (MVA Annual Meeting 2013)


          from Medicon Valley Alliance Added 34 0 0

          Watch the panel discussion about structural biology from Medicon Valley Alliance's 2013 Annual Meeting. Panellists: Bjørn Walse, CEO at SARomics Biostructures AB Esko Oksanen, Instrument…

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          • Revolutionary Biology Part 1: The building blocks of life


            from NDM Oxford Added 1,103 1 0

            Our bodies are made up of trillions of cells but it doesn’t matter how closely you look, you still won’t see them. In fact, most of our cells are smaller than the width of a hair. To…

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            • Yvonne Jones: Cancer and Protein Crystallography


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              Cells communicate through receptors on their surface; however, when these finely tuned systems don’t work correctly, diseases can be triggered. Professor Yvonne Jones has been working to identify…

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              • Conformational switch of the ryanodine receptor


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                Every single moment our life depends on the reliable functioning of muscles. Even slight malfunction of muscles results in diseases. To be able to treat and prevent muscle associated disease we need…

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                • Revolutionary Biology Part 2: The history of structural biology


                  from NDM Oxford Added 701 1 0

                  Understanding the function of a protein is an important step in finding out why the body succumbs to disease – but how do scientists find these proteins and figure out how they work?

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                  • Revolutionary Biology Part 4: A new age of drug discovery


                    from NDM Oxford Added 590 0 0

                    You just have to step into your local chemist to see how far medicine has come over the past 100 years. Life changing drugs, which were once unthinkable – like antibiotics, insulin and the contraceptive…

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                    • Panagis Filippakopoulos: Targeting epigenetics to treat cancer


                      from NDM Oxford Added 297 0 0

                      Professor Panagis Filippakopoulos from the Structural Genomics Consortium explains how we can target epigenetic mechanisms to treat cancer

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