1. Saquinavir-1ohr


    from Edgar Meyer / Added

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    Viracept (Saquinavir, Invirase) was designed on the basis of the structure the target enzyme, which mediates maturation of viral particles. When Viracept became available in 1995, the death rate from AIDS fell precipitously: http://www.nigms.nih.gov/Education/structure_drugs.htm Moreover, this historical event proved the undisputed merit of Structure-based Drug Design.

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