Elizabeth LaPensée's work addresses Indigenous determination in media such as games, animation, and web comics. She draws from her Irish, Anishinaabe, and Métis ancestors to inform her art, design, and writing.
Her web comic The West Was Lost (2008) was shown at imagineNATIVE 2010. Her experimental animation The Path Without End (2011) premiered at imagineNATIVE 2011. She contributed writing and consultation for the transmedia property Animism (2011). She has consulted and written for games such as Andy Schatz's Venture Arctic (2007).
She is Ph.D. (ABD) in Interactive Arts and Technology at Simon Fraser University. Her dissertation looks at the Indigenous social impact game Survivance (2011), which encourages healing through storytelling and art.
Her work is supported by the Aboriginal Territories in Cyberspace research network.